Designed by genetic counselors, for the complexity of real organizations

01

AI family history intake and pedigree creation

Incoming call from patient.0:00
0 relatives
Maternal sidePaternal sideAges and diagnoses
Voice call

Natural spoken intake on your organization's line, in the patient's own language.

Chat

The same intake as a conversation on the web, resumable at any point.

SMS

A secure link by text, answered from the phone already in hand.

To the organization

Arrives as a draft pedigree. Nothing enters the chart until the counselor approves it.

02

NCCN criteria and risk models, tied to the case

Try it, click any relativeno guidelines met
proband44
Sample for illustrative purposes0 relatives
National Comprehensive Cancer Network

Licensed by NCCN

LumaGen is an NCCN licensee and partner. The criteria you see come from the guidelines themselves, under license, and change when NCCN changes them.

Cancer Research UKUniversity of Oxford

Licensed for Tyrer-Cuzick

Licensed with Cancer Research UK and the University of Oxford, so the numbers you quote in clinic are the model itself, not an approximation of it.

National Cancer Institute

Aligned with the NCI

The Gail model is published by the National Cancer Institute as the Breast Cancer Risk Assessment Tool. We follow its implementation exactly.

03

Recontact, triggered by the guideline change itself

Recontact worklist17 open6 to call
Views
All open17
No email on file4
Awaiting response4
Attempted2
Reason
Reclassification5
Management change3
Testing criteria4
Family history5
Patient
Case
What changed
Contact
Outreach
Reclassification5 itemsPhone · worked one at a time
Nunez, Carol
2214870
RC-4412
BRCA2 c.5946delT
VUS → likely pathogenic
Email on file
Not started
Steinmetz, Rudolf
2176055
RC-4413
ATM c.7271T>G
VUS → pathogenic
No email on file
Not started
Okonkwo, Beatrice
2204551
RC-4401
CHEK2 c.1100delC
VUS → likely pathogenic
No email on file
Attempted, not reached
2 attempts · last 30 Aug
Testing criteria4 itemsEmail · worked as a batch
Vargas, Hector
2192271
TC-8841
Meets 2026 criteria
pancreatic + FDR breast <50
Email on file
Not started
Habib, Nasser
2219884
TC-8839
Meets 2026 criteria
prostate, Gleason ≥ 7
Email on file
Sent, awaiting response
batch 1 · 30 Aug
Grouped by reason, because a reclassification is a phone call and a criteria change is a batch. Nothing leaves the organization until a counselor releases it.Sample for illustrative purposes
Guideline revision

A criterion moves, and every family in the registry is scored against the new version.

Variant reclassified

An amended lab report arrives. The patients carrying that variant surface with the change attached.

Testing criteria update

The bar for who qualifies moves, and the patients who did not meet it before surface with the criterion they now meet.

LumaGen

A modern platform for the modern oncology clinician.

Draw one pedigree and see

© 2026 LumaGen, a product of Helix Reserve LLC|PrivacyTermsContactLumaGen supports clinical decisions. It does not make them, and it is not a diagnostic device.